Hot Sale Dorzolamide HCL (Generic) Ophthalmic Solution 2%

Dorzolamide is used as a treatment for glaucoma, and is often prescribed by veterinarians for use with dogs and cats. This drug contains a carbonic anhydrase inhibitor which decreases intraocular pressure, a characteristic of many types of glaucoma.

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Specifications

Uses

Dorzolamide HCl Ophthalmic Solution is indicated in the treatment of elevated intraocular pressure inpatients with ocular hypertension or open-angle glaucoma.

Possible Side Effects

The most frequently reported adverse reactions associated with Dorzolamide HCl Ophthalmic Solution were ocular burning, stinging, or discomfort immediately following ocular administration (approximately one-third of patients). Approximately one-quarter of patients noted a bitter taste following administration. Superficial punctate keratitis occurred in 10 to 15% of patients and signs and symptoms of ocular allergic reaction in approximately 10%.

Drug & Food Interactions

There is a potential for an additive effect on the known systemic effects of carbonic anhydraseinhibition in patients receiving an oral carbonic anhydrase inhibitor and Dorzolamide HCl OphthalmicSolution. The concomitant administration of Dorzolamide HCl Ophthalmic Solution and oral carbonicanhydrase inhibitors is not recommended.

Although acid-base and electrolyte disturbances were not reported in the clinical trials with Dorzolamide HCl Ophthalmic Solution, these disturbances have been reported with oral carbonic anhydrase inhibitors and have, in some instances, resulted in drug interactions (e.g., toxicity associatedwith high-dose salicylate therapy). Therefore, the potential for such drug interactions should be considered in patients receiving Dorzolamide HCl Ophthalmic Solution.

Precautions

Dorzolamide HCl Ophthalmic Solution contains dorzolamide, a sulfonamide; and although administered topically, it is absorbed systemically. Therefore, the same types of adverse reactions that are attributable to sulfonamides may occur with topical administration of Dorzolamide HCl Ophthalmic Solution.